Agents say they received a tip that Juanita McCurley of 179 Hunt Road in Thomas County was manufacturing the drug with a hand-held meth lab.
They say when they arrived at the house a burning smell tipped them off that drugs were actively being produced, and there was also evidence to show meth was being consumed.
Narcotics Commander Kevin Lee says investigators found a plate with already-processed meth on it inside the house.
McCurley was arrested for possession with intent to distribute methamphetamine.
Another woman at the house, Nancy Lindsey, was also charged with possession.
TCSO says one more arrest is pending in the case.