The most notable change is 30 chest compressions and then two breaths for adults, children and infants.
Previous guidelines called for 15 compressions at a time. The new policy also addresses the use of automated external defibrillators.
Officials say the guidelines should make teaching CPR easier.
Jeanine Hartin, training center coordinator, says, "The more simplification we can get of these guidelines, the universal approach, same number of compressions for adults, child and infant, then we can get more people trained, we can hit these 20 million people we want trained by 2010 and we can share with everyone and impact our entire community."
Training with the new guidelines should be in place by the spring though officials say learning CPR now can still help you save a life.