Fire officials say they received a call that people were trapped in a home.
When they arrived on scene they say the home was fully involved, but they were able to get everyone out safely.
Firefighters then attacked the fire; something they say is proving to be a challenge.
"We're just having a difficult time extinguishing the fire because it appears that maybe it was a mobile home that was surrounded by a brick exterior structure that had a roof on top of that,” explained Thomas County Fire Rescue Chris Jones.
Jones says the biggest issue is the fire trapped between the two roofs.
He says with the fire extinguished they will begin an investigation to determine the cause of the fire.
Firefighters say the house is a total loss.