Hearts pounding, blood pressure rising, and veins popping, week after week can take a toll.
College football coaches have more than game day rigors to contend with.
Their day to day coaching lives can become their everything.
"You have no life with your children," said former FSU coach Jim Gladden. "You have children who are playing sports or involved in school. You miss that. Somebody else is raising them. Your wife is teaching your son how to play football."
Gladden coached almost 30 years for the Noles.
He says those almost million dollar salaries for many coaches, add just as much stress as they do financial stability.
"There's tremendous pressure on these guys from boosters and fans and media. They're all resident experts and they want to critically analyze what you're doing wrong. When they pay you two million dollars, you better produce."
Florida football coach Urban Meyer cited health concerns for his first leave of absence. Michigan State's head coach Mark Dantonio, had a heart attack after a game in September.
"I can remember being absolutely physically ill the week of the Florida game. Just nauseous all the time getting ready for that game. The more successful you are, the more pressure there is."