Medical Minute 3-17: Prostate Cancer: Switching on Chemo

By: Melissa Medalie Email
By: Melissa Medalie Email

When Paul Roundy was diagnosed with prostate cancer five years ago, he approached it with the same determination that made him successful in business.

"Yes, I was very optimistic, although I was pretty much aware that prostate cancer does have a life of its own," said Paul Roundy.

After surgery and years of treatment, Paul's chemo stopped working.

"The problem with chemo is that many patients do not respond to chemotherapy in the first place, and the patients that do respond stop responding after certain duration of treatment," said Rakesh Singal, M.D., Medical Oncologist.

Doctor Rakesh Singal discovered a gene necessary for chemotherapy to work. It's often shut off in cancer cells. He's testing a drug that would trick the cancer cells into responding to chemo. In trials, patients get the drug called Vidaza daily for five days before chemo.

"So this drug turns the gene on and the chemotherapy starts working again," said Dr. Singal.

So far Paul's PSA -- a measure for prostate cancer -- dropped from about 30 to three.

"You can't feel it in your body, but you can see the results and see the numbers as they come out every three weeks as the PSA continues to lower," said Paul Roundy

Positive signs that prove his fight is headed in the right direction.

For more information: Ivanhoe Broadcast News2745 W. Fairbanks Ave.Winter Park, FL 32789http://www.ivanhoe.comMelissa Medalie, Supervising Producer Medical Newsmmedalie@ivanhoe.comDirect Line: (407) 691-1516Viewer Line: (407) 740-0789 ext. 579

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